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文章基本信息

  • 标题:Intragenic DNA methylation in buccal epithelial cells and intellectual functioning in a paediatric cohort of males with fragile X
  • 本地全文:下载
  • 作者:Marta Arpone ; Emma K. Baker ; Lesley Bretherton
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:3644
  • DOI:10.1038/s41598-018-21990-x
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:). Applying the WG method to the FXS cohort unmasked significant epi-genotype-phenotype relationships. These results extend previous evidence in blood to BEC and demonstrate FREE2 DNA methylation to be a sensitive epigenetic biomarker significantly associated with the variability in intellectual functioning in FXS.
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