摘要:= 0.7893 [negative mode], p-value < 0.00001). Based on the temporal profiles of the extracted metabolites by the model, results show only minimal deterioration of the plasma metabolome at -20 °C up to 1 month. However, majority of the changes appeared at around 12-15 days of storage. This allows scientists to better plan logistics and storage strategies for samples obtained from low-resource settings, where -80 °C storage is not guaranteed.