文章基本信息

标题：c-Jun N-terminal kinase 1 defective CD4+CD25+FoxP3+ cells prolong islet allograft survival in diabetic mice
本地全文：下载
作者：Deepak Tripathi ; Satyanarayana S. Cheekatla ; Padmaja Paidipally 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：3310
DOI：10.1038/s41598-018-21477-9
语种：English
出版社：Springer Nature
摘要：but not WT Tregs are able to inhibit IL-17 and IL-21 production through enhanced LAG-3 expression and IL-10 production. Our study identifies a novel role of JNK1 signaling in Tregs that enhances islet allograft survival in the liver parenchyma of CDM.