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  • 标题:Evaluation of HER2-specific peptide ligand for its employment as radiolabeled imaging probe
  • 本地全文:下载
  • 作者:Hadis Honarvar ; Enrica Calce ; Nunzianna Doti
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:2998
  • DOI:10.1038/s41598-018-21283-3
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:In-labeled A9 demonstrated nanomolar affinity to HER2-expressing BT474 cells and favorable biodistribution profile in NMRI mice. This study suggests that the peptide A9 represents a good lead candidate for development of molecular probe, to be used for imaging purposes and for the delivery of cytotoxic agents.
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