文章基本信息

标题：Salt-bridge modulates differential calcium-mediated ligand binding to integrin α1- and α2-I domains
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作者：Kyle L. Brown ; Surajit Banerjee ; Andrew Feigley 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：2916
DOI：10.1038/s41598-018-21231-1
语种：English
出版社：Springer Nature
摘要：binding affinity while increasing binding to collagen ligands 20%. These data indicate the E152-R192 salt bridge is a key distinction in the molecular mechanism of differential ion binding of these two I domains.