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  • 标题:Synthetic Whole-Cell Biodevices for Targeted Degradation of Antibiotics
  • 本地全文:下载
  • 作者:Peng-Fei Xia ; Qian Li ; Lin-Rui Tan
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:2906
  • DOI:10.1038/s41598-018-21350-9
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:promoters conferred resistance up to 50 μg/mL of tetracycline and degrades over 95% of tetracycline within 24 h. The detoxification ability of tetX was further verified in conditioned media by typical E. coli K-12 and B strains as well as Shewanella oneidensis. Our strategy demonstrated the feasibility of introducing genetic modules into model hosts to enable environmental functions, and this work will inspire more environmental innovations through synthetic biological devices.
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