文章基本信息

标题：TRPA1-dependent reversible opening of tight junction by natural compounds with an α,β-unsaturated moiety and capsaicin
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作者：Yusuke Kanda ; Youhei Yamasaki ; Yoshie Sasaki-Yamaguchi 等
期刊名称：Scientific Reports
电子版ISSN：2045-2322
出版年度：2018
卷号：8
期号：1
页码：2251
DOI：10.1038/s41598-018-20526-7
语种：English
出版社：Springer Nature
摘要：influx and TJ permeability increase not only by an α,β-unsaturated compound but also by capsaicin. Our results indicate that the α,β-unsaturated moiety can be a potent pharmacophore for TJ opening.