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  • 标题:Demonstration of ion channel synthesis by isolated squid giant axon provides functional evidence for localized axonal membrane protein translation
  • 本地全文:下载
  • 作者:Chhavi Mathur ; Kory R. Johnson ; Brian A. Tong
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:2207
  • DOI:10.1038/s41598-018-20684-8
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:currents increased in both cases; with added inactivation kinetics on those axons injected with RNA encoding the Shaker channel. These results provide unambiguous evidence that isolated axons can exhibit de novo synthesis, assembly and membrane incorporation of fully functional oligomeric membrane proteins.
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