首页    期刊浏览 2024年11月24日 星期日
登录注册

文章基本信息

  • 标题:Early Detection of Apathetic Phenotypes in Huntington’s Disease Knock-in Mice Using Open Source Tools
  • 本地全文:下载
  • 作者:Shawn Minnig ; Robert M. Bragg ; Hardeep S. Tiwana
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:2304
  • DOI:10.1038/s41598-018-20607-7
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:mice exhibit reduced PR performance at 9-11 months of age, suggesting motivational deficits. We replicated this in two independent cohorts, demonstrating the reliability and utility of both the apathetic phenotype, and these ROBuckets, for preclinical HD studies.
国家哲学社会科学文献中心版权所有