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  • 标题:Antimicrobial activity of Ti-ZrN/Ag coatings for use in biomaterial applications
  • 本地全文:下载
  • 作者:Anthony J. Slate ; David J. Wickens ; Mohamed El Mohtadi
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:1497
  • DOI:10.1038/s41598-018-20013-z
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:values. An increase in dead Staphylococcus aureus and Staphylococcus epidermidis cells was observed on the coatings with a higher silver concentration. Using CTC staining, a significant increase in S. aureus respiration on the silver containing surfaces was observed in comparison to the stainless steel control whilst against S. epidermidis, no significant difference in viable cells was observed across the surfaces. Cytotoxicity testing revealed that the TiZrN coatings, both with and without varying silver concentrations, did not possess a detrimental effect to a human monocyte cell line U937. This work demonstrated that such coatings have the potential to reduce the viability of bacteria that result in pin tract infections.
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