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文章基本信息

  • 标题:Loss of disease tolerance during Citrobacter rodentium infection is associated with impaired epithelial differentiation and hyperactivation of T cell responses
  • 本地全文:下载
  • 作者:Eugene Kang ; Guangyan Zhou ; Mitra Yousefi
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:847
  • DOI:10.1038/s41598-017-17386-y
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:T cell activation through increased antigen processing and presentation were specifically associated with the response to infection in susceptible mice. These data provide insights into the molecular mechanisms underlying intestinal dysfunction and disease tolerance during C. rodentium infection.
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