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  • 标题:Exploring the utility of alcohol flushing as an instrumental variable for alcohol intake in Koreans
  • 本地全文:下载
  • 作者:Yoonsu Cho ; Soyoung Kwak ; Sarah J. Lewis
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2018
  • 卷号:8
  • 期号:1
  • 页码:458
  • DOI:10.1038/s41598-017-18856-z
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:). An increase in alcohol intake, as predicted by both the absence of alcohol flushing and the presence of the rs671 GG genotype in the IV analyses, was associated with an increase in blood pressure in men from this Korean population. In conclusion, this study supports a causal effect of alcohol intake on hypertension and indicated that alcohol flushing may be a valid proxy for the ALDH2 rs671 polymorphism, which influences alcohol intake in this Korean population.
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