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  • 标题:Lysine-Specific Demethylase 1 (LSD1/KDM1A) Is a Novel Target Gene of c-Myc
  • 本地全文:下载
  • 作者:Mai Nagasaka ; Kaori Tsuzuki ; Yu Ozeki
  • 期刊名称:Biological and Pharmaceutical Bulletin
  • 印刷版ISSN:0918-6158
  • 电子版ISSN:1347-5215
  • 出版年度:2019
  • 卷号:42
  • 期号:3
  • 页码:481-488
  • DOI:10.1248/bpb.b18-00892
  • 出版社:The Pharmaceutical Society of Japan
  • 摘要:Grammatical metaphor refers to depicting the same scenes or things in the objective world with different forms of expression. It mainly includes two parts: interpersonal metaphor and ideational metaphor. Interpersonal metaphor is divided into metaphors of mood and metaphors of modality. Metaphors of mood are the transfer from one modal domain to another. The metaphors of modality change from implicit to explicit and reflect in the form of proposition. Language not only has the function of expressing the speaker's personal experience and inner activity, but also can express the speaker's identity, attitude, motivation and his/her inference, judgment and evaluation of things. Therefore, based on the frequency of the use of interpersonal metaphor, the reader can accurately grasp the information exchanged by the speakers. This paper applies interpersonal metaphor to analyze the discourses of the main characters in Tess of the D'Urbervilles by using declarative which is used as command as well as question; interrogative, which is used as command as well as statement, etc. in metaphors of mood and using the subjective explicit as well as objective explicit in metaphors of modality. Through the different expressions of the character discourse, speech function embodied in the discourse is interpreted to help the reader understand the theme of the text more easily, thereby revealing the pragmatic value of interpersonal metaphor in the analysis of literary works.
  • 关键词:c-Myc;lysine-specific demethylase 1;The Cancer Genome Atlas (TCGA) database
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