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  • 标题:Nobiletin induces growth inhibition and apoptosis in human nasopharyngeal carcinoma C666‐1 cells through regulating PARP‐2/SIRT1/AMPK signaling pathway
  • 本地全文:下载
  • 作者:Guo Dong Zheng ; Ping Jun Hu ; Ying Xin Chao
  • 期刊名称:Food Science & Nutrition
  • 电子版ISSN:2048-7177
  • 出版年度:2019
  • 卷号:7
  • 期号:3
  • 页码:1104-1112
  • DOI:10.1002/fsn3.953
  • 出版社:John Wiley & Sons, Ltd.
  • 摘要:Strong claims are made regarding the significant role that multiword sequences play in the comprehension and production of speech and writing. Although the literature is replete with research-informed, evidence-based guidelines on how to maximize the learning of such sequences, such guidelines need to be synthesized, analyzed and evaluated for learning purposes. This paper attempts to fill this gap, addressing the numerous instructional options that ESL/EFL practitioners, curriculum designers and materials authors have at their disposal while dealing with lexically bundled sequences in several learning contexts. Another purpose of this paper, is to explain the problems that may arise as a result of teaching these sequences and the ways to solve them. The bulk of discussion will be centered on the tasks, activities and techniques suggested by researchers for deepening learners’ understanding of these patterns across a wide range of contexts.
  • 关键词:AMPK ;apoptosis;C666‐1;nobiletin;PARP‐2
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