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  • 标题:Predicting Long-Term Cardiovascular Events after Transient Ischemic Attacks: Carotid Artery Intima-Media Thickness or ABCD2 Score or Both?
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  • 作者:Fariborz Khorvash ; Helia Hemasian ; Shahab Shahabi
  • 期刊名称:INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE
  • 印刷版ISSN:2008-7802
  • 出版年度:2018
  • 卷号:9
  • 页码:102
  • DOI:10.4103/ijpvm.IJPVM_415_17
  • 语种:English
  • 出版社:ISFAHAN UNIVERSITY OF MEDICAL SCIENCES
  • 摘要:Background: Patients who experienced transient ischemic attack (TIA) are at high-risk for cardiovascular events. This study aims to evaluate diagnostic value of carotid artery intima-media thickness (CIMT) and ABCD2 score for predicting cardiovascular events in long-term follow-up after TIA. We prospectively included sixty patients with TIA who admitted to hospital from March 2016 to August 2016. Methods: Duplex ultrasonography of internal carotid arteries was performed. ABCD2 scores were evaluated for each patient. At a median follow-up of 20 months, patients were asked about new cardiovascular events. We used IBM SPSS software version 22.0 with Chi-squared, t -test, ANOVA, receiver operating characteristic, and area under the curve (AUC) analysis for our work. Results: Sensitivity and negative predictive value of the combined score (ABCD2+CIMT) was the highest (96.3% and 90.9%, respectively), and the specificity and positive predictive value of the CIMT were the highest (57.5% and 63.1%, respectively) to predict cardiovascular events in long-term. Conclusion: Compared to ABCD2 score, CIMT proved to be more accurate to predict cardiovascular events in long-term follow-ups (AUC = 0.736 vs. AUC = 0.640). However, adding CIMT value to ABCD2 score was even better (AUC = 0.750). Therefore, CIMT measurement in the ABCD2 score after TIA enables prediction of long-term cardiovascular events.
  • 关键词:Area under curve ; carotid intima-media thickness ; receiver operating characteristic curve ; stroke ; transient ischemic attack
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