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文章基本信息

  • 标题:Hyperglycemia aggravates microenvironment hypoxia and promotes the metastatic ability of pancreatic cancer
  • 本地全文:下载
  • 作者:Wei Li ; Han Liu ; Weikun Qian
  • 期刊名称:Computational and Structural Biotechnology Journal
  • 印刷版ISSN:2001-0370
  • 出版年度:2018
  • 卷号:16
  • 页码:479-487
  • DOI:10.1016/j.csbj.2018.10.006
  • 语种:
  • 出版社:Computational and Structural Biotechnology Journal
  • 摘要:Background Diabetes mellitus and pancreatic cancer are intimately related. Our previous studies showed that high levels of blood glucose promote epithelial-mesenchymal transition of pancreatic cancer. In this study, we evaluated the relationship between hyperglycemia and hypoxic tumor microenvironments.
  • 关键词:Hyperglycemia ; Hypoxia ; HIF-1α ; Metastasis ; Pancreatic cancer
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