期刊名称:Computational and Structural Biotechnology Journal
印刷版ISSN:2001-0370
出版年度:2016
卷号:14
页码:69-77
DOI:10.1016/j.csbj.2015.10.006
语种:
出版社:Computational and Structural Biotechnology Journal
摘要:With next generation sequencing thousands of virus and viral vector integration genome targets are now under investigation to uncover specific integration preferences and to define clusters of integration, termed common integration sites (CIS), that may allow to assess gene therapy safety or to detect disease related genomic features such as oncogenes.
关键词:Gene therapy ; Systems biology ; Genomics ; Insertional mutagenesis