标题:KENeV: A web-application for the automated reconstruction and visualization of the enriched metabolic and signaling super-pathways deriving from genomic experiments
期刊名称:Computational and Structural Biotechnology Journal
印刷版ISSN:2001-0370
出版年度:2015
卷号:13
页码:248-255
DOI:10.1016/j.csbj.2015.03.009
语种:
出版社:Computational and Structural Biotechnology Journal
摘要:Gene expression analysis, using high throughput genomic technologies,has become an indispensable step for the meaningful interpretation of the underlying molecular complexity, which shapes the phenotypic manifestation of the investigated biological mechanism. The modularity of the cellular response to different experimental conditions can be comprehended through the exploitation of molecular pathway databases, which offer a controlled, curated background for statistical enrichment analysis. Existing tools enable pathway analysis, visualization, or pathway merging but none integrates a fully automated workflow, combining all above-mentioned modules and destined to non-programmer users.