期刊名称：Computational and Structural Biotechnology Journal
印刷版ISSN：2001-0370
出版年度：2014
卷号：11
期号：18
页码：11-21
DOI：10.1016/j.csbj.2014.09.002
语种：
出版社：Computational and Structural Biotechnology Journal
摘要：Cellular signal transduction is a complex phenomenon, which plays a central role in cell surviving and adaptation. The great amount of molecular data to date present in literature, together with the adoption of high throughput technologies, on the one hand, made available to scientists an enormous quantity of information, on the other hand, failed to provide a parallel increase in the understanding of biological events. In this context, a new discipline arose, the systems biology, aimed to manage the information with a computational modeling-based approach. In particular, the use of biological networks has allowed the making of huge progress in this field.
关键词：Systems biology ; Biological networks ; Network topology ; Signal transduction ; Spermatozoa ; Endocannabinoid system
