期刊名称:Computational and Structural Biotechnology Journal
印刷版ISSN:2001-0370
出版年度:2012
卷号:3
期号:4
DOI:10.5936/csbj.201210008
语种:
出版社:Computational and Structural Biotechnology Journal
摘要:Biotechnology research is traditionally focused on individual microbial strains that are perceived to have the necessary metabolic functions, or the capability to have these functions introduced, to achieve a particular task. For many important applications, the development of such omnipotent microbes is an extremely challenging if not impossible task. By contrast, nature employs a radically different strategy based on synergistic combinations of different microbial species that collectively achieve the desired task. These natural communities have evolved to exploit the native metabolic capabilities of each species and are highly adaptive to changes in their environments. However, microbial communities have proven difficult to study due to a lack of suitable experimental and computational tools.