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  • 标题:Frequency and associated risk factors of non-fatal overdose reported by pregnant women with opioid use disorder
  • 本地全文:下载
  • 作者:Sarah M. Bagley ; Howard Cabral ; Kelley Saia
  • 期刊名称:Addiction Science & Clinical Practice
  • 电子版ISSN:1940-0640
  • 出版年度:2018
  • 卷号:13
  • 期号:1
  • 页码:26
  • DOI:10.1186/s13722-018-0126-0
  • 语种:English
  • 出版社:BioMed Central
  • 摘要:Little is known about opioid overdose or naloxone access among pregnant women. The objectives of this study were to determine the prevalence of non-fatal overdose, risk factors for overdose, and naloxone access among third trimester women in treatment for opioid use disorder. We collected baseline data from a case management parental-support intervention study. To explore the association of variables with past year overdose, we used Wilcoxon rank-sum test, Chi square or Fisher’s exact tests. Among 99 participants, 14% (95% CI 7–21%) reported past year overdose and 67% (95% CI 57–76%) had received overdose education and a naloxone kit. Younger age was the only variable associated with past year overdose. In this sample, past year non-fatal overdose was common, younger age was a risk factor, and most participants had received a naloxone kit. Further work is needed to understand whether younger age is a risk factor in the general population of pregnant women with opioid use disorder and to identify other potential risk factors for overdose in this population.
  • 关键词:Opioids ; Overdose ; Pregnancy ; Naloxone
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