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  • 标题:Platelet-rich plasma intra-articular injections as an alternative treatment for knee osteoarthritis: a systematic review
  • 本地全文:下载
  • 作者:Elena Sîrbu ; Șerban Gligor ; Corina Pantea
  • 期刊名称:Timisoara Physical Education and Rehabilitation Journal
  • 印刷版ISSN:2065-0574
  • 出版年度:2017
  • 卷号:10
  • 期号:19
  • 页码:46-51
  • DOI:10.1515/tperj-2017-0015
  • 语种:English
  • 出版社:Walter de Gruyter GmbH
  • 摘要:Knee osteoarthritis is a degenerative joint disease characterized by cartilage degeneration and hypertrophic lesions of the epiphyseal bone. It is a disabling condition that causes difficulties of locomotion and severe complications in case of inappropriate treatment. There is growing evidence proving the beneficial effects of using platelet-rich plasma (PRP) in the treatment of knee osteoarthritis. The aim of the present paper is to review the recent scientific literature on the treatment of knee osteoarthritis with platelet-rich plasma presenting the current opinion on this subject. Methods : We analys several studies about PRP who were identified using online databases: EBSCO, ScienceDirect, Scopus and PubMed. Results: After the primary analysis we selected a total of 23 relevant studies. The analysis focused on different PRP administration techniques and methods used in knee osteoarthritis. Conclusions: PRP is most widely used in incipient and moderate symptomatic knee osteoarthritis. Most studies show a significant decrease in pain and significant improvement in joint functionality. These results were mostly obtained after a short follow-up period (6 months-1 year) and also this treatment has a small number of side effects.
  • 关键词:platelet-rich plasma (PRP) ; knee osteoarthritis ; pain ; function ; range of motion
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