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  • 标题:randomizeR: An R Package for the Assessment and Implementation of Randomization in Clinical Trials
  • 本地全文:下载
  • 作者:Diane Uschner ; David Schindler ; Ralf-Dieter Hilgers
  • 期刊名称:Journal of Statistical Software
  • 印刷版ISSN:1548-7660
  • 电子版ISSN:1548-7660
  • 出版年度:2018
  • 卷号:85
  • 期号:1
  • 页码:1-22
  • DOI:10.18637/jss.v085.i08
  • 语种:English
  • 出版社:University of California, Los Angeles
  • 摘要:Randomization in clinical trials is the key design technique to ensure the comparability of treatment groups. Although there exist a large number of software products which assist the researcher to implement randomization, no tool which would cover a wide range of procedures and allow the comparative evaluation of the procedures under practical restrictions has been proposed in the literature so far. The R package randomizeR addresses this need. The paper includes a detailed description of the randomizeR package that serves as a tutorial for the generation of randomization sequences and the assessment of randomization procedures.
  • 其他关键词:clinical trial;restricted randomization;selection bias;chronological bias;R
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