摘要：Emerging pollutants are increasingly detected in aqueous environmental samples, with pharmaceuticals and related compounds consisting a large category with many diverse groups, including parent compounds and their metabolites/transformation products. Significant research is performed on this subject worldwide, in order to obtain information regarding their occurrence, fate and health effects. In this effort, development and optimization of highly sensitive and accurate analytical methods for their determination in environmental samples is a necessity, but also a challenge. Advanced analytical methods for emerging pollutants include liquid chromatography (LC) or gas chromatography (GC) followed by tandem mass spectrometric (MS/MS) detection. These methods, combined with a variety of sample preparation procedures, provide the ability to analyze emerging pollutants in the environment in trace levels, and to identify and quantify their oxidation/degradation products. However, there are still many analytical aspects that need improvement and optimization for increasing the accuracy and sensitivity of the methods, in order to be able to fill the gaps of knowledge on the studied compounds.
