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  • 标题:Comparison of Retinal Ganglion Cell Damage in Glaucoma and Retinal Vein Occlusion by Visual Field
  • 本地全文:下载
  • 作者:Lee, Jiyoung ; Jeon, Sooji ; Park, Hae-Young Lopilly
  • 期刊名称:Journal of the Korean Ophthalmological Society
  • 印刷版ISSN:0378-6471
  • 出版年度:2019
  • 卷号:60
  • 期号:5
  • 页码:455-462
  • DOI:10.3341/jkos.2019.60.5.455
  • 出版社:The Korean Ophthalmological Society
  • 摘要:Purpose

    We analyzed and compared retinal ganglion cell damage between patients with glaucoma and those with branched retinal vein occlusion (BRVO). We performed two types of visual field examinations.

    Methods

    We retrospectively reviewed the medical records of 40 glaucoma eyes and 40 BRVO eyes. We compared the median deviation (MD), the pattern standard deviation (PSD), and sensitivity of damaged visual hemifield from frequency-doubling technology (FDT) C24-2 and standard automated perimetry (SAP) C24-2 visual field tests evaluation. We sought correlations between the MDs and retinal nerve fiber layer thickness as revealed by optical coherence tomography.

    Results

    MDs did not differ between the groups. PSD value was higher in glaucoma patients with FDT C24-2 test ( p = 0.022), but no difference between two groups with SAP C24-2 test ( p = 0.144). In terms of the sensitivity of the damaged visual hemifield, glaucoma patients had larger areas of damage in the FDT C24-2 test ( p < 0.01). In regression analyses, the log R2 values of both tests were higher in glaucoma patients.

    Conclusions

    Glaucoma patients had a greater damaged visual field area in the FDT C24-2 test than the SAP C24-2 test. The BRVO patients exhibited similar extents of damage in both tests. Thus, the subtypes and distributions of damaged retinal ganglion cells may differ between the conditions, facilitating differential diagnosis.

  • 关键词:Glaucoma; Retinal ganglion cell; Retinal vein occlusion; Visual field
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