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  • 标题:A simple mathematical model for Guillain–Barré syndrome
  • 本地全文:下载
  • 作者:Mohammed Fathy Elettreby ; Elsayed Ahmed ; Muntaser Safan
  • 期刊名称:Advances in Difference Equations
  • 印刷版ISSN:1687-1839
  • 电子版ISSN:1687-1847
  • 出版年度:2019
  • 卷号:2019
  • 期号:1
  • 页码:1-18
  • DOI:10.1186/s13662-019-2146-9
  • 出版社:Hindawi Publishing Corporation
  • 摘要:In this paper, four different forms of a model to describe the dynamics of autoimmune diseases (with emphasis on Guillain–Barré syndrome) are proposed. In the first two cases, the immune response is supposed to be linear, while in the other two cases it is supposed to be in the Holling type III form. In case of linear immune response, the model has a basic reproduction number and shows forward bifurcation. However, in the nonlinear Holling type III immune response cases, the model does not have a basic reproduction number and two positive equilibria do exist for a range of the parameters. The stability analysis of the model’s steady states has been established. Our analytical results have been illustrated by numerical simulations.
  • 关键词:Guillain–Barré syndrome ; Steady states ; Stability analysis ; Tolerance ; Flare-up ; Dormancy
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