In this paper, we investigated the mechanics and permeation properties of the raw coal sample during loading and unloading process, and come to some conclusions: the permeability of the sample increases nonlinearly during the unloading confining pressure process. The larger the gas pressure is, the greater the increase range of the permeability will be. The larger the confining pressure unloading amplitude is, the greater the increase range of the permeability will be. In the loading process, the permeability and the axial strain of the specimen change in a “V” shape. As the gas pressure increases, the peak strength of the specimen gradually decreases, and fitted the gas pressure and the peak strength are accordance with the linear relationship. As the confining pressure increase, the peak strength of the sample gradually increases, and fitted the confining pressure and the peak strength are accordance with the exponential function. The internal friction angle of the coal sample was 43.22°, and the cohesion was 3.77 MPa. The relationship between the fitted gas pressure and internal friction angle, gas pressure and cohesion is in line with linear functions. Maintain an axial stress constant, unloaded confining pressure to a constant state of target value, the permeability of specimen shows a constant pressure boosting flow zone, the relationship between permeability and deviatoric stress is accordance with the ExpDec1 function during the process of unloading confining pressure and prepeak loading axial stress.