文章基本信息
- 标题：A therapeutic method for the direct reprogramming of human liver cancer cells with only chemicals
- 本地全文：下载
- 作者：Hisashi Moriguchi ; Yue Zhang ; Makoto Mihara 等
- 期刊名称：Scientific Reports
- 电子版ISSN：2045-2322
- 出版年度：2012
- 卷号：2
- 期号：1
- DOI：10.1038/srep00280
- 语种：English
- 出版社：Springer Nature
- 摘要：
Various methods for the direct reprogramming of human somatic cells have been developed. However, a therapeutic method to reprogram and eliminate human solid tumor cells has not been developed. Here we show a novel therapeutic method to reprogram and eliminate human solid tumor cells with chemicals. This therapeutic method may be applicable to various human solid tumor cells that express aldo-keto reductase family 1 member B10 (AKR1B10) and retinoid X receptors (RXRs).
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