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  • 标题:A new computational approach to estimate whole-brain effective connectivity from functional and structural MRI, applied to language development
  • 本地全文:下载
  • 作者:Gerald Hahn ; Michael A. Skeide ; Dante Mantini
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2019
  • 卷号:9
  • 期号:1
  • 页码:1-13
  • DOI:10.1038/s41598-019-44909-6
  • 出版社:Springer Nature
  • 摘要:Recently introduced effective connectivity methods allow for the in-vivo investigation of large-scale functional interactions between brain regions. However, dynamic causal modeling, the most widely used technique to date, typically captures only a few predefined regions of interest. In this study, we present an alternative computational approach to infer effective connectivity within the entire connectome and show its performance on a developmental cohort with emerging language capacities. The novel approach provides new opportunities to quantify effective connectivity changes in the human brain.
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