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  • 标题:Number of sons contributes to ageing-associated inflammation
  • 本地全文:下载
  • 作者:Saara Marttila ; Tapio Nevalainen ; Laura Kananen
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2015
  • 卷号:5
  • 期号:1
  • DOI:10.1038/srep08631
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:The rate of inflammation increases in elderly individuals, a phenomenon called inflammaging, and is associated with degenerative diseases. However, the causes of inflammaging and the origin of the associated inflammatory mediators have remained enigmatic. We show herein that there is a positive correlation between the number of sons born and C-reactive protein concentrations in 90-year-old women. This association is influenced by HLA genetics known to regulate the immune response against HY antigens.
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