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  • 标题:Characterization of the Transcriptional Complexity of the Receptive and Pre-receptive Endometria of Dairy Goats
  • 本地全文:下载
  • 作者:Lei Zhang ; Xiao-Peng An ; Xiao-Rui Liu
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2015
  • 卷号:5
  • 期号:1
  • DOI:10.1038/srep14244
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:Endometrium receptivity is essential for successful embryo implantation in mammals. However, the lack of genetic information remains an obstacle to understanding the mechanisms underlying the development of a receptive endometrium from the pre-receptive phase in dairy goats. In this study, more than 4 billion high-quality reads were generated and de novo assembled into 102,441 unigenes; these unigenes were annotated using published databases. A total of 3,255 unigenes that were differentially expressed (DEGs) between the PE and RE were discovered in this study ( P -values ADCY8, VCAN, SPOCK1, THBS1 , and THBS2 may play important roles in the development of endometrial receptivity. The de novo assembly provided a good starting point and will serve as a valuable resource for further investigations into endometrium receptivity in dairy goats and future studies on the genomes of goats and other related mammals.
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