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  • 标题:Effects of Scorpion venom peptide B5 on hematopoietic recovery in irradiated mice and the primary mechanisms
  • 本地全文:下载
  • 作者:Caixia Wang ; Meixun Zhou ; Ting Li
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2015
  • 卷号:5
  • 期号:1
  • DOI:10.1038/srep15363
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:Scorpion venom peptide B5 (SVP-B5) stimulates recovery of hematopoiesis after exposure to radiation. However, its radioprotective effects and mechanisms are still unclear. The aim of this study was to investigate the effects of SVP-B5 on hematopoietic recovery in mice after total body irradiation (TBI) at a dose of 7.5Gy and 6Gy and to explore the possible primary mechanisms. SVP-B5 at a dose of 2.63 μg/kg significantly reduced the mortality rate of mice after TBI (p
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