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  • 标题:The Argi system: one-step purification of proteins tagged with arginine-rich cell-penetrating peptides
  • 本地全文:下载
  • 作者:Filip Bartnicki ; Piotr Bonarek ; Ewa Kowalska
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2017
  • 卷号:7
  • 期号:1
  • DOI:10.1038/s41598-017-02432-6
  • 语种:English
  • 出版社:Springer Nature
  • 摘要:The discovery of cell penetrating peptides (CPPs) opened new perspectives for the delivery of proteins into human cells. It is considered that in the future CPP-mediated transport of therapeutic proteins may find applications in the treatment of human diseases. Despite this fact a fast and simple method for the purification of CPP-tagged proteins, free of additional tags, was not available to date. To fill this gap we developed the Argi system for one-step purification of proteins tagged with arginine rich CPPs.
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