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  • 标题:Optimization of Supercritical CO2 Fluid Extraction of Flavonoids from Spina Gleditsiae by Response Surface Method
  • 本地全文:下载
  • 作者:Xiaojuan Liu ; Xia Gao
  • 期刊名称:IOP Conference Series: Earth and Environmental Science
  • 印刷版ISSN:1755-1307
  • 电子版ISSN:1755-1315
  • 出版年度:2019
  • 卷号:242
  • 期号:4
  • 页码:1-7
  • DOI:10.1088/1755-1315/242/4/042015
  • 出版社:IOP Publishing
  • 摘要:In order to optimize the supercritical CO2 fluid extraction of flavonoids from spina gleditsiae, single-factor experiments were utilized to investigate the influences of the extraction temperature, extraction pressure, and entrainment dosage firstly. Then the optimal extraction process for flavonoids extraction was determined by response surface methodology and the quadratic mathematical model was established which reliability was finally verified. The optimal supercritical CO2 fluid extraction conditions were as follows: entrainment dosage of 36mL, extraction temperature of 48°Cand extraction pressure of 40Mpa. Under this condition, the yield of flavonoids from spina gleditsiae was 0.793%.
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