期刊名称：IOP Conference Series: Earth and Environmental Science
印刷版ISSN：1755-1307
电子版ISSN：1755-1315
出版年度：2019
卷号：252
期号：2
页码：1-5
DOI：10.1088/1755-1315/252/2/022084
出版社：IOP Publishing
摘要：The invention relate to 1, 2-dihydroazete-3-methyl ester and a series of derivatives, which can be used to treat cardiovascular diseases and hepatitis c virus (HCV). This research mainly describe a synthesis route of the key intermediate for synthetizing Forskolin and HCV NS5B inhibitors. The synthesis routes is mainly consist of three steps of acylation, replacement and hydrolysis. This synthesis route provides some valuable references and experimental basis for the synthesis of Forskolin and HCV NS5B inhibitors.
