摘要:International Journal of Exercise Science 12(1): 950-959, 2019. Following anterior cruciate ligament reconstruction, individuals experience inadequate functioning of the quadriceps and decreased muscular strength. Decreased function delays return to physical activity and increases potential for re-injury. While several squat variations exist, a new variation has emerged in rehabilitation. The purpose of this study was to compare muscle activation of the Vastus Lateralis (VL), Vastus Medialis (VM), Rectus Femoris (RF), Gluteus Maximus (GM), and anterior posterior center of pressure (AP displacement) alterations during a single leg squat variation (SLS variation) versus a traditional split squat using electromyography (EMG) in healthy active females. Seventeen females performed one set of both squat variations on a force plate while muscle activation was measured. Paired t-tests were used to compare dependent variable (DV) means between squat variations. Results indicated SLS variation yielded lower peak and mean quadriceps activation compared to traditional split squat, (p < 0.05). However, peak and mean GM muscle activity was greater in the SLS variation compared to the traditional split squat, (p < 0.01). Lastly, AP displacement was greater during the SLS variation, (p < 0.001). All three quadricep muscles had greater peak and mean EMG suggesting the traditional split squat be used for quadricep activation in rehabilitation/training settings, while the SLS variation should be prescribed for greater GM muscle activation. Understanding muscle activation patterns amongst squat variations can be practically applied by therapists, coaches and trainers to aid in reducing risks of arthrokinetic dysfunction via synergistic dominance, faster return to physical activity and normal functions of daily activity.