期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:2019
卷号:116
期号:26
页码:12613-12614
DOI:10.1073/pnas.1907920116
出版社:The National Academy of Sciences of the United States of America
摘要:Velavan et al. (1) describe work that they have carried out based on our recent PNAS publication, “Mutations in Plasmodium falciparum actin-binding protein coronin confer reduced artemisinin susceptibility” (2). Among 297 patient samples from 4 countries in Africa, they found 12 polymorphic amino acid sites in Pf Coronin, 7 observed only among 48 parasites from the Congo (1). These findings are consistent with results reported in the Pf3k database (https://www.malariagen.net/projects/p-falciparum-communityproject), which we referenced in our original publication. The amino acid replacements of Pf Coronin that we found to be .