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  • 标题:Genetic diversity of feline leukemia virus
  • 本地全文:下载
  • 作者:A K Komina ; A D Zaberezhny ; O D Kucheruk
  • 期刊名称:IOP Conference Series: Earth and Environmental Science
  • 印刷版ISSN:1755-1307
  • 电子版ISSN:1755-1315
  • 出版年度:2019
  • 卷号:315
  • 期号:4
  • 页码:1-5
  • DOI:10.1088/1755-1315/315/4/042038
  • 出版社:IOP Publishing
  • 摘要:Feline Leukemia Virus (FeLV) belongs to retrovirus family, causing various proliferative and immunosuppressive diseases in felines. There are two forms of FeLV: endogenous (enFeLV) and exogenous (exFeLV), the latter has 4 subgroups: A, B, C and T with different receptor specificity. The FeLV-A is the most abundant transmissive form. The FeLVB emerged as a recombinant between provirus FeLV-A and endogenous virus of domestic cats. The FeLV-C appeared as a result of accumulation of mutations in the env FeLV-A gene. The chimeric FeLV-T virus was obtaind as recombination event between 61E and 61C viruses. This review also covers two new recently described subgroups - FeLV-D и TG35.
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