首页    期刊浏览 2024年12月03日 星期二
登录注册

文章基本信息

  • 标题:A Novel α-Glucosidase of the Glycoside Hydrolase Family 31 from Aspergillus sojae
  • 本地全文:下载
  • 作者:Atsushi Kawano ; Yuji Matsumoto ; Nozomi Nikaido
  • 期刊名称:Journal of Applied Glycoscience
  • 印刷版ISSN:1344-7882
  • 电子版ISSN:1880-7291
  • 出版年度:2019
  • 卷号:66
  • 期号:2
  • 页码:73-81
  • DOI:10.5458/jag.jag.JAG-2018_0012
  • 出版社:The Japanese Society of Applied Glycoscience
  • 摘要:

    We characterized an α-glucosidase belonging to the glycoside hydrolase family 31 from Aspergillus sojae. The α-glucosidase gene was cloned using the whole genome sequence of A. sojae , and the recombinant enzyme was expressed in Aspergillus nidulans . The enzyme was purified using affinity chromatography. The enzyme showed an optimum pH of 5.5 and was stable between pH 6.0 and 10.0. The optimum temperature was approximately 55 °C. The enzyme was stable up to 50 °C, but lost its activity at 70 °C. The enzyme acted on a broad range of maltooligosaccharides and isomaltooligosaccharides, soluble starch, and dextran, and released glucose from these substrates. When maltose was used as substrate, the enzyme catalyzed transglucosylation to produce oligosaccharides consisting of α-1,6-glucosidic linkages as the major products. The transglucosylation pattern with maltopentaose was also analyzed, indicating that the enzyme mainly produced oligosaccharides with molecular weights higher than that of maltopentaose and containing continuous α-1,6-glucosidic linkages. These results demonstrate that the enzyme is a novel α-glucosidase that acts on both maltooligosaccharides and isomaltooligosaccharides, and efficiently produces oligosaccharides containing continuous α-1,6-glucosidic linkages.

  • 关键词:α-glucosidase;Aspergillus;glycoside hydrolase family 31;transglucosylation
国家哲学社会科学文献中心版权所有