Understanding the stress‐cracks‐permeability evolution law inside coal body under cyclic loading is significant to optimize the gas extraction technology and gas disasters prevention technology. In order to explore the influence of mining cyclic stress on the mechanical behavior and permeability variation of gas‐bearing seams, the experiments on permeability evolution, deformation law, and acoustic emission (AE) characteristics of coal samples under cyclic loading with different loading stress level and different loading frequency were carried out. These results indicate that the higher loading stress level, the shorter the fatigue life of coal sample. With the increase of the loading stress level, the change rate of permeability became higher and the relation curves between permeability and loading cycles developed from “U” to “V,” which can be defined and divided into three stages, for example, decrease stage, stable stage, and increase stage. And the permeability in the decrease stage can be modeled as a power function of the loading cycles, while the permeability in the increase stage can be modeled as an exponential function of the loading cycles. Besides, the loading stress level has a significant on the permeability, while the loading frequency has little impact on the permeability evolution. In the process of coal deformation under cyclic loading, the strain development of strain coal samples was in the shape of inverted “S,” while the variation of the peak values of corresponding AE ring counts presented “U” type. In addition, there was a good correlation between the permeability and the AE parameters of coal samples, which provide a new sight into the dynamic variation process of the stress‐cracks‐permeability evolution inside coal body under cyclic loading.