标题：Multinutrients from Local Cattle Bone Marrow in Central Sulawesi of Indonesia Have the Potential to Improve the Successful Pregnancy Rate and Prevent Slowing of Fetal Kidney Growth
摘要：Background and Objective: The results of previous studies have indicated that undernutrition that occurs during pregnancy can result in the slowing of fetal growth. Intrauterine growth retardation (IUGR) caused by malnutrition will have a negative effect on organogenesis, including kidney growth (nephrogenesis). This study aimed to evaluate the potency of bone marrow obtained from a local beef livestock practice in Central Sulawesi of Indonesia to increase the success of pregnancy and to prevent the slowing of fetal kidney growth during pregnancy. Materials and Methods: This experimental laboratory study with animal models used a complete randomized design (CRD) with a single factor. The bone marrow was obtained from the Tawanjuka Palu slaughterhouse of Central Sulawesi in Indonesia. A standard feed, an intrauterine growth retardation feed and a substitution isocaloric feed with bone marrow were formulated. The intervention was applied to rats during pregnancy with the feed available ad libitum . After birth, the offspring underwent lactation until the age of 22 days and then weaned and given standard feed. At the age of 30 days, the kidneys were removed and weighed. The kidney weight data were analyzed using a descriptive statistical test and a Wilcoxon test using SPSS version 23. Results: The results of the descriptive analysis indicate that there was a positive trend in response to the feed with the bone marrow but Wilcoxon analysis showed no significant difference in kidney weight between the control and intervention groups. Conclusion: Feed formulations containing bone marrow from local cattle have the potential to prevent slowing of kidney growth during pregnancy and increase the success of pregnancy.
关键词：Local beef; local cattle bone marrow; mother's nutrition; slowing kidney growth; successful pregnancy
