Background: The Pediatric Symptom Checklist-Youth Version (PSC-Y) is a widely used self-report measure designed to detect psychosocial dysfunctions in adolescents and youth. PSC-Y has been translated and validated in different languages. However, Hindi translation, as well as psychometric validation of PSC-Y, is yet to be done in India. Therefore, the objective of the present study was to translate the PSC-Y in Hindi language and psychometrically validate it in Indian setting. Method: To ascertain the psychometric properties; the Hindi version of PSC-Y, the Mental Health Inventory, the Adjustment Inventory, and the Hospital Anxiety and Depression Scale were administered to 300 secondary and higher secondary students of different schools of Varanasi and nearby places. Furthermore, after one month the Hindi translated version of PSC-Y was re-administered on 178 students. Results: Findings of the present study suggest that the Hindi version of PSC-Y has high test-retest reliability (r= 0.82, p< 0.01), and strong internal consistency (Cronbach α = 0.84, p < 0.01; Spearman-Brown r = 0.82, p< 0.01). The concurrent validity of the tool is also good, along with its sensitivity and specificity in detecting anxiety, depression and general mental health. Conclusion: The Hindi version of PSC-Y has good psychometric properties and further it can be used for the screening of the psychosocial dysfunctions among Indian adolescents.