期刊名称:Proceedings of the National Academy of Sciences
印刷版ISSN:0027-8424
电子版ISSN:1091-6490
出版年度:2020
卷号:117
期号:2
页码:816-817
DOI:10.1073/pnas.1915295117
出版社:The National Academy of Sciences of the United States of America
摘要:In Cudini et al. (1), the authors suggest that earlier work has argued high levels of intrahost variation in human cytomegalovirus (HCMV) to be the result of exceptionally fast mutation rates (on par with RNA viruses), citing our recent review (2) as evidence. In reality, ref. 2 noted that levels of variation can be comparable to those observed in certain RNA viruses (as Cudini et al. reconfirm), and that this required explanation “in light of the low mutation rates of herpesviruses relative to those of RNA viruses.” In the summarized primary literature, ref. 3 argued that fast mutation rates could explain … [↵][1]1To whom correspondence may be addressed.