We described a wireless and monitoring system to obtain several classes of vehicle data and send them to the server via General Packet Radio Service (GPRS) in real-time. These data are consisted by on-board diagnostic (OBD) which get from the vehicle’s OBD interface, Tire-Pressure Monitoring system (TPMS) and Global Positioning System (GPS). The main content of this paper is the hardware design of the system, especially RF modules and antennas.