标题：The rationale of opportunistic bilateral salpingectomies (OBS) during benign gynaecological and obstetric surgery: a consensus text of the Flemish Society of Obstetrics and Gynaecology (VVOG)
摘要：Ovarian cancer (OC), is a disease difficult to diagnose in an early stage implicating a poor prognosis. The 5-year
overall survival in Belgium has not changed in the last 18 years and remains 44 %. There is no effective screening
method (secondary prevention) to detect ovarian cancer at an early stage. Primary prevention of ovarian cancer
came in the picture through the paradigm shift that the fallopian tube is often the origin of ovarian cancer and
not the ovary itself. Opportunistic bilateral salpingectomy (OBS) during benign gynaecological and obstetric
surgery might have the potential to reduce the risk of ovarian cancer by as much as 65 %. Bilateral risk-reducing
salpingectomy during a benign procedure is feasible, safe, appears to have no impact on the ovarian function and
seems to be cost effective. The key question is whether we should wait for a RCT or implement OBS directly in our
daily practice. Guidelines regarding OBS within our societies are therefore urgently needed. Our recommendation
is to inform all women without a child wish, undergoing a benign gynaecological or obstetrical surgical procedure
about the pro’s and the con’s of OBS and advise a bilateral salpingectomy. Furthermore, there is an urgent need
for a prospective registry of OBS. The present article is the consensus text of the Flemish Society of Obstetrics and
Gynaecology (VVOG) regarding OBS.
