期刊名称:Annals of Agricultural and Environmental Medicine
印刷版ISSN:1232-1966
电子版ISSN:1898-2263
出版年度:2018
卷号:25
期号:2
页码:1-7
DOI:10.26444/aaem/82624
出版社:Institute of Agricultural Medicine in Lublin
摘要:Introduction and objective. Hungary is one of the areas in Europe most infected with ragweed (Ambrosia artemisiifolia L.)
and its pollen, and is the most important cause of seasonal allergic rhinoconjunctivitis in the country. The aim of the study
was to investigate the association between ragweed pollen allergy and long-term ragweed pollen load, as well as analysis
of the the impacts of additional potential risk factors on health outcomes.
Materials and method. A modified version of standardized questionnaires, based on the International Study of Asthma and
Allergy in Childhood, were completed by the parents of schoolchildren aged 8 – 9 attending 3rd grade classes throughout
the country. Pollen load was calculated for each settlement from daily ragweed pollen concentrations monitored by 19
monitoring stations in the country. Descriptive and analytical statistical methods were applied.
Results. At national level there was a significant inverse association between prevalence of ragweed allergy and its pollen
load, but significance was lost after excluding data from Budapest, the capital city, due to the impact of urbanization. In
the adjusted model, parental atopic disease was the strongest risk factor (either parent had atopic disease aOR=2.60; 95%
CI=2.31–2.93 or both parents had atopic disease aOR=4.56; 95% CI=3.71–5.60). Further significant risk factors were male
gender (aOR=1.52; 95% CI=1.36–1.71), lower respiratory infection in the first two years of life (aOR=1.91; 95% CI=1.70–2.16),
and unshared children’s room (aOR=1.22; 95% CI=1.09–1.37). Allergy was significantly less common among children whose
parents received social aid (aOR=0.83; 95% CI=0.72–0.97) and whose mother smoked during pregnancy (aOR=0.80; 95%
CI=0.64–0.99).
Conclusions. Higher ragweed pollen exposure was not found to be associated with higher risk of ragweed allergy.
关键词:children; infection; risk factor; prevalence; pollen load; common ragweed