期刊名称：Annals of Agricultural and Environmental Medicine
印刷版ISSN：1232-1966
电子版ISSN：1898-2263
出版年度：2018
卷号：25
期号：3
页码：1-4
DOI：10.26444/aaem/91467
出版社：Institute of Agricultural Medicine in Lublin
摘要：Introduction. Hepatitis A (HA) is caused by infection with the hepatitis A virus (HAV). The differential etiological diagnosis of
acute hepatitis is based on a positive result of the serological test detecting IgM class anti-HAV. For epidemiological studies
on past infection and seroprevalence of HAV in populations, the tests measuring IgG class anti-HAV or total anti-HAV are
used. Since the 1990s, specific prophylaxis is possible by vaccination against HA. In Poland, vaccination is recommended
and in majority is performed at own cost.
Materials and method. Database was obtained from electronic medical records of the 2 major private health care providers
networks (Luxmed and Medicover) operating in Poland. During a 3-year period (2013–2015), 1,124 persons with unknown
status of anti-HA vaccination were tested for the presence of total anti-HAV.
Objective. The aim of the study was to evaluate the seroprevalence of anti-HAV among working professionals in Poland.
Results. Anti-HAV were detected in 603 (53.6%) persons, while 521 (46.3%) tested negative. The study group was divided
into 2 subgroups: 25–44 and 45–64-years-old. For detailed statistical analysis, the presence of anti-HAV was considered as
a dependent variable, and its predictors were gender, age and the year of the test performance. The presence of anti-HAV
was significantly more prevalent in older age group. The lack of specific antibodies was more prevalent in younger age
group.
Conclusions. Results of the study show increasing susceptibility to HAV infection in the younger age group, compared with
the older age group of corporate professional employees in large cities in Poland. Since the epidemiological situation of HA
is currently changing with increasing number of symptomatic cases of HA, it is suggested that employers might consider
including an additional procedure of vaccination against HA into their private health insurance portfolio.
关键词：hepatitis A; hepatitis A antibodies seroprevalence; vaccination against hepatitis type A
