期刊名称：Annals of Agricultural and Environmental Medicine
印刷版ISSN：1232-1966
电子版ISSN：1898-2263
出版年度：2019
卷号：26
期号：1
页码：1-6
DOI：10.26444/aaem/93747
出版社：Institute of Agricultural Medicine in Lublin
摘要：Introduction and objectives. Insect stings are the second trigger of anaphylaxis in children and adolescents, causing a
potentially life-threatening reactions. Hence health-related quality of life (HRQoL) is an important issue for Hymenoptera
venom allergy (HVA) patients. The aim of this cross-sectional study was to evaluate the impact of HVA on young patients’
HRQoL, including their socio-demographic characteristics.
Materials and method. The study sample included 102 patients aged 8–17 (Mean 12.5 years, SD=3.0), who were under
diagnosis or venom immunotherapy due to systemic reaction after an insect sting in one of the tertiary referential centers
in Poland. They were mostly boys (70%), and mainly from rural areas (63%). HRQoL of studied patients was measured with
the Children’s Hymenoptera Venom Allergy Quality of Life Scale, a questionnaire covering 6 dimensions: anxiety, caution,
limitations, discomfort, support received from parents and a feeling of safety, each measured from 1 to 5. Independent
predictors of HRQoL were estimated using the Generalized Linear Model.
Results. In the group of children being dermal reactors, girls reported a higher level of anxiety (B=1.17, 95%CI=(0.30;2.03),
p=0.008). In the group of children with grade 2 it was the girls who reported lower anxiety (B=-1.33, 95%CI=(-2.38;-0.29),
p=0.013). Boys treated longer than 3 years had their level of anxiety significantly lower than those studied at diagnosis
(B=-0.65, 95%CI=(-1.23;-0.07), p=0.028). The feeling of safety was higher in children living in villages than in those living in
towns (B=0.30, 95%CI=(0.03;0.56), p=0.031).
Conclusions. The gender, treatment duration and stage of anaphylactic reaction influenced level of anxiety. The level of
feeling of safety was related to the place of living.
关键词：health;related quality of life; children; adolescents; insect sting; Hymenoptera venom allergy; cross;sectional study
