期刊名称：Journal of Materials and Environmental Science
印刷版ISSN：2028-2508
出版年度：2019
卷号：10
期号：1
页码：1-6
出版社：University of Mohammed Premier Oujda
摘要：A new derivatives 6-arylamino-5-cyano-2,3-dihydro-1,3-thiazin-4(1H)-ones is designed
as potential antifungal agents. Synthesis of 6-arylamino-5-cyano-2,3-dihydro-1,3-
thiazin-4(1H)-ones s was carried out by the condensation of 3-arylamino-2-cyano-3-
mercapto-acrylamides with various aldehydes under microwave irradiation using and
lemon juice as a natural catalyst and solvent. Synthesized compounds were
characterized on the basis of IR, 1
HNMR, 13CNMR, mass and analytical data. Some of
synthesized compounds were screened in vitro for antifungal activity by inhibitory
action against four fungal strains like Fusarium oxysporum, Aspergillus niger,
Verticillium dahliae and Aspergillus flavus . Most of the synthesized compounds have
shown good antifungal activities.
关键词：Microwave
; Green synthesis; 1;3-thiazines; Lemon juice; Antifungal
