摘要：With the increasing side effects and decreasing effectiveness of synthetic drugs with time, trend has been moving
towards the use of natural and safe drugs with less or no side effects and equal effective like synthetic drugs for curing
diseases. So, in this view the present research has been done to investigate the antioxidant and first time the anticancer
property of Sesbania aculeata. Plant belongs to legume family and is mainly grown for green manure. Extracts of
different parts of the plant were prepared by using Soxhlet apparatus and methanol was used as choice of solvent. The
antioxidant activity was checked by four different methods including DPPH free-radical scavenging, hydrogen peroxide
scavenging activity, hydroxyl radical scavenging activity and iron reducing power FRAP. The anticancer activity was
checked by using SRB assay against the human lung cancer cell line Hop-62. Extracts of all the tested parts of Sesbania
aculeata showed excellent in vitro antioxidant activity with maximum activity of about 71-76% in seed coat extract
when checked with different methods. Similarly, the seeds coat extracts exhibit anticancer potential against the tested
cancer cell line while other parts showed negligible activity. The results have shown that the methanolic extracts could
be the source of potential antioxidant and anticancer agents.
